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Babes RM, Selescu T, Domocos D, Babes A. "The anthelminthic drug praziquantel is a selective agonist of the sensory transient receptor potential melastatin type 8 channel". Toxicol Appl Pharmacol. 2017 Dec 1;336:55-65.[LINK]

Babes A, Ciotu CI, Hoffmann T, Kichko TI, Selescu T, Neacsu C, Sauer SK, Reeh PW, Fischer MJM. Photosensitization of TRPA1 and TRPV1 by 7-dehydrocholesterol: implications for the Smith-Lemli-Opitz syndrome. Pain. 2017 Dec;158(12):2475-2486.[LINK]



Kistner K, Siklosi N, Babes A, Khalil M, Selescu T, Zimmermann K, Wirtz S, Becker C, Neurath MF, Reeh PW, Engel MA. "Systemic desensitization through TRPA1 channels by capsazepine and mustard oil - a novel strategy against inflammation and pain." Sci Rep. 2016 Jun 30;6:28621.[LINK]

Babes A, Sauer SK, Moparthi L, Kichko TI, Neacsu C, Namer B, Filipovic M, Zygmunt PM, Reeh PW, Fischer MJ. "Photosensitization in Porphyrias and Photodynamic Therapy Involves TRPA1 and TRPV1." J Neurosci. 2016 May 11;36(19):5264-78. [LINK]

Ciobanu AC, Selescu T, Gasler I, Soltuzu L, Babes A. "Glycolytic metabolite methylglyoxal inhibits cold and menthol activation of the transient receptor potential melastatin type 8 channel". J Neurosci Res. 2016 Mar 94(3):282-94. Epub 2015 Dec 2. [LINK]

Khalil M, Babes A, Lakra R, Försch S, Reeh PW, Wirtz S, Becker C, Neurath MF, Engel MA. "Transient receptor potential melastatin 8 ion channel in macrophages modulates colitis through a balance-shift in TNF-alpha and interleukin-10 production".Mucosal Immunol. 2016 Nov 9(6):1500-1513.[LINK]


Eberhardt M, Dux M, Namer B, Miljkovic J, Cordasic N, Will C, Kichko TI, de la Roche J, Fischer M, Suárez SA, Bikiel D, Dorsch K, Leffler A, Babes A, Lampert A, Lennerz JK, Jacobi J, Martí MA, Doctorovich F, Högestätt ED, Zygmunt PM, Ivanovic-Burmazovic I, Messlinger K, Reeh P, Filipovic MR. "H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway". Nat Commun. 2014 15;5:4381.[LINK]

Cucu D, Chiritoiu G, Petrescu S, Babes A, Stanica L, Duda DG, Horii A, Dima SO, Popescu I. "Characterization of Functional Transient Receptor Potential Melastatin 8 Channels in Human Pancreatic Ductal Adenocarcinoma Cells". Pancreas. 2014 43(5):795-800. [LINK]


Selescu T, Ciobanu AC, Dobre C, Reid G, Babes A. "Camphor Activates and Sensitizes Transient Receptor Potential Melastatin 8 (TRPM8) to Cooling and Icilin". Chem Senses. 38(7): 563-75. [LINK]

Babes A, Fischer MJ, Filipovic M, Engel MA, Flonta ML, Reeh PW. "The anti-diabetic drug glibenclamide is an agonist of the transient receptor potential Ankyrin 1 (TRPA1) ion channel". Eur J Pharmacol. 704(1-3): 15-22. [LINK]


Bierhaus A, Fleming T, Stoyanov S, Leffler A, Babes A, Neacsu C, Sauer SK, Eberhardt M, Schnölzer M, Lasischka F, Neuhuber WL, Kichko TI, Konrade I, Elvert R, Mier W, Pirags V, Lukic IK, Morcos M, Dehmer T, Rabbani N, Thornalley PJ, Edelstein D, Nau C, Forbes J, Humpert PM, Schwaninger M, Ziegler D, Stern DM, Cooper ME, Haberkorn U, Brownlee M, Reeh PW, Nawroth PP. "Methylglyoxal modification of Na(v)1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy." Nature Medicine 2012 18(6): 926-33. [LINK]


Engel, M.A., Leffler, A., Niedermirtl, F., Babes, A., Zimmermann, K., Filipovi, M.R., Izydorczyk, I., Eberhardt, M., Kichko, T.I., Muellertribbensee, S.M., Khalil, M., Siklosi, N., Nau, C., Ivanoviburmazovi, I., Neuhuber, W.L., Becker, C., Neurath, M.F., Reeh, P.W. "TRPA1 and substance P mediate colitis in mice" Gastroenterology 2011 141(4): 1346-1358. [LINK]

Babes, A., Ciobanu, A. C., Neacsu, C., Babes, R. M. "TRPM8, a Sensor for Mild Cooling in Mammalian Sensory Nerve Endings", Current Pharmaceutical Biotechnology 2011 12(1): 78-88. [LINK]


Neacsu, C., Babes, A. (2010), "The M-channel blocker linopirdine is an agonist of the capsaicin receptor TRPV1", Journal of Pharmacological Sciences 114(3): 332-340. [LINK]

Babes, A., Fischer, M.J., Reid, G., Sauer, S.K., Zimmermann, K., Reeh, P.W. (2010), "Electrophysiological and neurochemical techniques to investigate sensory neurons in analgesia research." Methods in molecular biology (Clifton, N.J.) 617: 237-259. [LINK]

Neacsu, C., Ciobanu, C., Barbu, I., Toader, O., Szegli, G., Kerek, F., Babes, A. (2010), "Substance MCS-18 isolated from Helleborus purpurascens is a potent antagonist of the capsaicin receptor, TRPV1, in rat cultured sensory neurons", Physiological Research 59(2): 289-298. [LINK]


Ciobanu C., Reid G, Babes A. (2009), "Acute and chronic effects of neurotrophic factors BDNF and GDNF on responses mediated by thermo-sensitive TRP channels in cultured rat dorsal root ganglion neurons.", Brain Research 1284: 54-67. [LINK]


Zimmermann, K., Leffler, A., Babes, A., Cendan, C. M., Carr, R. W., Kobayashi, J., Nau, C., Wood, J. N., Reeh, P. (2007), "Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures", Nature 447(7146): 855 - 859. [LINK]

Leffler, A., Linte, R., Nau, C., Reeh, P., Babes, A. (2007), "A high-threshold heat-activated channel in cultured rat dorsal rot ganglion neurons resembles TRPV2 and is blocked by gadolinium", European Journal of Neuroscience 26(1): 12-22. [PDF]

Linte, R.M., Ciobanu, C., Reid, G., Babes, A. (2007) "Desensitization of cold- and menthol-sensitive rat dorsal root ganglion neurones by inflammatory mediators". Experimental Brain Research 178(1): 89-98. [PDF]


Babes A, Zorzon D, Reid G. (2006) "A novel type of cold-sensitive neuron in rat dorsal root ganglia with rapid adaptation to cooling stimuli" Eur J Neurosci. 24(3): 691-8. [PDF]


Babes, A., Zorzon, D., Reid, G. (2004) "Two populations of cold-sensitive neurons in rat dorsal root ganglia and their modulation by nerve growth factor" Eur. J. Neurosci. 20: 2276-2282. [PDF]


Reid, G., Babes, A., Pluteanu, F. (2002) "A cold- and menthol-activated current in rat dorsal root ganglion neurones: properties and role in cold transduction" J. Physiol. 545.2: 595-614. [PDF]

Pluteanu, F., Ristoiu, V., Flonta, M.-L., Reid, G. (2002) "a1-adrenoceptor-mediated depolarization and b-mediated hyperpolarization in cultured rat dorsal root ganglion neurones" Neurosci. Lett. 329: 277-280. [PDF]

Ristoiu, V., Pluteanu, F., Flonta, M.-L., Reid, G. (2002) "Few cultured rat primary sensory neurons express a tolbutamide-sensitive K+ current" J. Cell. Mol. Med. 6: 271-274. [PDF]

Reid, G. and Flonta, M.-L. (2002) "Ion channels activated by cold and menthol in cultured rat dorsal root ganglion neurones" Neurosci. Lett. 324: 164-168. [PDF]

Babes, A., Amuzescu, B., Krause, U., Scholz, A., Flonta, M.-L. and Reid, G. (2002) "Cooling inhibits capsaicin-induced currents in cultured rat dorsal root ganglion neurones" Neurosci. Lett. 317: 131-134. [PDF]


Babes, A., Lörinczi, E., Ristoiu, V., Flonta, M.-L. and Reid, G. (2001) "Slowing of inactivation at positive potentials in a rat axonal K+ channel is not due to preferential closed-state inactivation: differences between inactivation of native and cloned K+ channels." Physiol. Res. 50: 557-565. [PDF]

Reid, G., Flonta, M.-L. (2001) "Cold current in thermoreceptive neurons." Nature 413(6855): 480. [PDF]

Reid, G., Amuzescu, B., Zech, E. and Flonta, M.-L. (2001) "A system for applying rapid warming or cooling stimuli to cells during patch clamp recording or ion imaging." J. Neurosci. Methods 111: 1-8. [PDF]

Reid, G., Flonta, M.-L. (2001) "Cold transduction by inhibition of a background potassium conductance in rat primary sensory neurones" Neurosci. Lett. 297: 171-174. [PDF]


Babes, A., Fendler, K. (2000) "Na+ transport, and the E1P-E2P conformational transition of the Na+/K+-ATPase" Biophys. J. 79: 2557-2571.


Reid, G., Scholz, A., Bostock, H., Vogel, W. (1999) "Human axons contain at least five types of voltage-dependent potassium channel"
J. Physiol. 518: 681-696. [PDF]

Ganea, C., Babes, A., Lupfert, C., Grell, E., Fendler, K., Clarke, R.J. (1999) "Hofmeister effects of anions on the kinetics of partial reactions of the Na+/K+-ATPase" Biophys. J. 77: 267-281.