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PN-III-P4-ID-PCE-2016-0475

Molecular targets responsible for the pain associated with neurovisceral porphyrias

Project director: Prof. Dr. Alexandru Babes, University of Bucharest

ISI Journals

Babes RM, Selescu T, Domocos D, Babes A. "The anthelminthic drug praziquantel is a selective agonist of the sensory transient receptor potential melastatin type 8 channel". Toxicol Appl Pharmacol. 2017 Dec 1;336:55-65.[LINK]

Babes A, Ciotu CI, Hoffmann T, Kichko TI, Selescu T, Neacsu C, Sauer SK, Reeh PW, Fischer MJM. Photosensitization of TRPA1 and TRPV1 by 7-dehydrocholesterol: implications for the Smith-Lemli-Opitz syndrome. Pain. 2017 Dec;158(12):2475-2486.[LINK]

 

Tinte moleculare responsabile de durerea asociata cu porfiriile neuroviscerale

Director proiect: Prof. Dr. Alexandru Babes, Universitatea din Bucuresti